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DeCS
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Descriptor English:
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RNA Interference
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Descriptor Spanish:
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Interferencia de ARN
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Descriptor Portuguese:
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Interferência de RNA
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Synonyms English:
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Co-Suppression
Cosuppression
Posttranscriptional Gene Silencing
RNA Silencing
RNAi
Co Suppression
Gene Silencing, Post Transcriptional
Gene Silencing, Posttranscriptional
Gene Silencings, Posttranscriptional
Interference, RNA
Post Transcriptional Gene Silencing
Post-Transcriptional Gene Silencings
Silencing, Post-Transcriptional Gene
Gene Silencing, Post-Transcriptional
Post-Transcriptional Gene Silencing
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Tree Number:
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G05.308.203.374.790
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Definition English:
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A gene silencing phenomenon whereby specific dsRNAs (RNA, DOUBLE-STRANDED) trigger the degradation of homologous mRNA (RNA, MESSENGER). The specific dsRNAs are processed into SMALL INTERFERING RNA (siRNA) which serves as a guide for cleavage of the homologous mRNA in the RNA-INDUCED SILENCING COMPLEX. DNA METHYLATION may also be triggered during this process. |
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See Related English:
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RNA, Small Interfering
RNA-Induced Silencing Complex
RNAi Therapeutics
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History Note English:
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2003
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Allowable Qualifiers English:
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Record Number:
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37644
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Unique Identifier:
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D034622
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Occurrence in VHL:
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Similar:
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DeCS CID-10 LILACS
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